Upregulation of Aryl Hydrocarbon Receptor in Granulosa Cells by Endoplasmic Reticulum Stress Contributes to the PCOS Pathophysiology

Studies have demonstrated that endocrine disrupting chemicals (EDC) are involved in the pathophysiology of PCOS, and aryl hydrocarbon receptor (AHR) mediates the cellular effect of EDC by inducing xenobiotic metabolizing enzymes including cytochrome P450 1B1 (CYP1B1). However, recent studies suggest...

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Detalles Bibliográficos
Publicado en:J Endocr Soc
Autores principales: Kunitomi, Chisato, Harada, Miyuki, Azhary, Jerilee M K, Kusamoto, Akari
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2021
Materias:
Reproductive Endocrinology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266198/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1573
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