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Upregulation of Aryl Hydrocarbon Receptor in Granulosa Cells by Endoplasmic Reticulum Stress Contributes to the PCOS Pathophysiology

Studies have demonstrated that endocrine disrupting chemicals (EDC) are involved in the pathophysiology of PCOS, and aryl hydrocarbon receptor (AHR) mediates the cellular effect of EDC by inducing xenobiotic metabolizing enzymes including cytochrome P450 1B1 (CYP1B1). However, recent studies suggest...

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Bibliografische gegevens
Gepubliceerd in:J Endocr Soc
Hoofdauteurs: Kunitomi, Chisato, Harada, Miyuki, Azhary, Jerilee M K, Kusamoto, Akari
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266198/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1573
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