Upregulation of Aryl Hydrocarbon Receptor in Granulosa Cells by Endoplasmic Reticulum Stress Contributes to the PCOS Pathophysiology

Studies have demonstrated that endocrine disrupting chemicals (EDC) are involved in the pathophysiology of PCOS, and aryl hydrocarbon receptor (AHR) mediates the cellular effect of EDC by inducing xenobiotic metabolizing enzymes including cytochrome P450 1B1 (CYP1B1). However, recent studies suggest...

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Veröffentlicht in:J Endocr Soc
Hauptverfasser: Kunitomi, Chisato, Harada, Miyuki, Azhary, Jerilee M K, Kusamoto, Akari
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Reproductive Endocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8266198/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1573
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