MON-089 Discovery and Identification of Late Stage Selective Nonpeptide Somatostatin Subtype 5 (sst5) Agonists for the Treatment of Hyperinsulinemic Hypoglycemia

Congenital hyperinsulinism (CHI) results from mutations within the insulin secretion pathway and is characterized by excessive and/or inappropriate insulin secretion by pancreatic islet β-cells. CHI is the most common cause of persistent hypoglycemia in newborns and infants and is estimated to affec...

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Foilsithe in:J Endocr Soc
Main Authors: Fowler, Melissa A, Zhao, Jian, Sturchler, Emmanuel, Rico, Elizabeth, de Necochea-Campion, Rosalia, Athanacio, Jon, Kredel, Taylor A, Antwan, Agnes, Johns, Michael, Tsivkovski, Oleg, Wang, Shmiao, Luo, Rosa, Kusnetzow, Ana Karin, Madan, Ajay, Struthers, Scott, Markison, Stacy, Zhu, Yun Fei, Betz, Stephen F
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2020
Ábhair:
Pediatric Endocrinology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208924/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.701
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