SUN-LB39 ATAC-Seq Reveals Dynamic Changes in Chromatin Accessibility Following PKA Activation in NCI-H295R Adrenocortical Cells

The adrenal cortex is comprised of distinct concentric zones that produce hormones essential for life - the outermost zona glomerulosa (zG) produces aldosterone, and the innermost zona fasciculata (zF) produces cortisol. Adrenal zonation is maintained by a balance between paracrine (Wnt/β-catenin) a...

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Bibliographic Details
Published in:J Endocr Soc
Main Authors: LaPensee, Christopher Ryan, Mohan, Dipika, Lerario, Antonio Marcondes, Hammer, Gary D
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Adrenal
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208637/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.2316
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