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SUN-LB119 Role of HNF4a Isoforms in the Carbohydrate/Lipid Switch in the Liver and Responsiveness to AMPK

Hepatocyte Nuclear Factor 4α (HNF4α), the master regulator of liver-specific gene expression, is regulated by two promoters (P1 and P2) which drive expression of two groups of HNF4α isoforms referred to here as HNF4α1 and HNF4α7. HNF4α is a known regulator of gluconeogenesis and is mutated in maturi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Endocr Soc
Hauptverfasser: Radi, Sarah, Deol, Poonamjot, Deans, Jonathan Robert, Fekry, Baharan, Eckel-Mahan, Kristin, Sladek, Frances M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7208273/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvaa046.2263
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