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Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer
HNF4α has been implicated in colitis and colon cancer in humans but the role of the different HNF4α isoforms expressed from the two different promoters (P1 and P2) active in the colon is not clear. Here, we show that P1-HNF4α is expressed primarily in the differentiated compartment of the mouse colo...
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| Pubblicato in: | eLife |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4907689/ https://ncbi.nlm.nih.gov/pubmed/27166517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10903 |
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