Conditioned medium from M2b macrophages modulates the proliferation, migration, and apoptosis of pulmonary artery smooth muscle cells by deregulating the PI3K/Akt/FoxO3a pathway

BACKGROUND: Immunity and inflammation are considered to be central features of pulmonary artery hypertension (PAH), in which macrophages are one of the main components of inflammatory cell infiltration around the pulmonary artery. M2b macrophages, which are different from M1 and M2 macrophages, are...

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Publicado en:PeerJ
Autores principales: Huang, Suiqing, Yue, Yuan, Feng, Kangni, Huang, Xiaolin, Li, Huayang, Hou, Jian, Yang, Song, Huang, Shaojie, Liang, Mengya, Chen, Guangxian, Wu, Zhongkai
Formato: Artigo
Lenguaje:Inglês
Publicado: PeerJ Inc. 2020
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7207208/
https://ncbi.nlm.nih.gov/pubmed/32411539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.9110
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