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PDE3 Inhibition Reduces Epithelial Mast Cell Numbers in Allergic Airway Inflammation and Attenuates Degranulation of Basophils and Mast Cells

Epithelial mast cells are generally present in the airways of patients with allergic asthma that are inadequately controlled. Airway mast cells (MCs) are critically involved in allergic airway inflammation and contribute directly to the main symptoms of allergic patients. Phosphodiesterase 3 (PDE3)...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Pharmacol
Prif Awduron: Beute, Jan, Ganesh, Keerthana, Nastiti, Hedwika, Hoogenboom, Robin, Bos, Vivica, Folkerts, Jelle, Schreurs, Marco W. J., Hockman, Steve, Hendriks, Rudi W., KleinJan, Alex
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206980/
https://ncbi.nlm.nih.gov/pubmed/32425769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00470
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