Loading...
Deficiency of TGR5 exacerbates immune-mediated cholestatic hepatic injury by stabilizing the β-catenin destruction complex
Intrahepatic cholestasis induced by drug toxicity may cause cholestatic hepatic injury (CHI) leading to liver fibrosis and cirrhosis. The G protein-coupled bile acid receptor 1 (TGR5) is a membrane receptor with well-known roles in the regulation of glucose metabolism and energy homeostasis. However...
Na minha lista:
| Udgivet i: | Int Immunol |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2020
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7206975/ https://ncbi.nlm.nih.gov/pubmed/31930324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxaa002 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|