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Endoplasmic reticulum resident oxidase ERO1-Lalpha promotes hepatocellular carcinoma metastasis and angiogenesis through the S1PR1/STAT3/VEGF-A pathway

Mounting evidence demonstrates that expression of ERO1α, an endoplasmic reticulum (ER)-resident oxidase, is a poor prognosis factor in a variety of human cancers. However, the clinical relevance of ERO1α and its molecular mechanisms underlying tumor progression have not been determined for hepatocel...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Yang, Shikun, Yang, Chao, Yu, Fei, Ding, Wenbing, Hu, Yuanchang, Cheng, Feng, Zhang, Feng, Guan, Bugao, Wang, Xuehao, Lu, Ling, Rao, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207574/
https://ncbi.nlm.nih.gov/pubmed/30377291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1134-4
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