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Endoplasmic Reticulum Oxidoreductin-1-Like β (ERO1lβ) Regulates Susceptibility to Endoplasmic Reticulum Stress and Is Induced by Insulin Flux in β-Cells
Hyperglycemia increases insulin flux through the endoplasmic reticulum (ER) of pancreatic β-cells, and the unfolded protein response pathway is required to enhance insulin processing. Pancreatic and duodenal homeobox 1 (PDX1), a key pancreatic transcription factor, regulates insulin along with targe...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Endocrine Society
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3115612/ https://ncbi.nlm.nih.gov/pubmed/21540283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-1420 |
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