Photoswitchable ORG25543 Congener Enables Optical Control of Glycine Transporter 2

[Image: see text] Glycine neurotransmission in the dorsal horn of the spinal cord plays a key role in regulating nociceptive signaling, but in chronic pain states reduced glycine neurotransmission is associated with the development of allodynia and hypersensitivity to painful stimuli. This suggests...

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Publicado en:ACS Chem Neurosci
Autores principales: Mostyn, Shannon N., Sarker, Subhodeep, Muthuraman, Parthasarathy, Raja, Arun, Shimmon, Susan, Rawling, Tristan, Cioffi, Christopher L., Vandenberg, Robert J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2020
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206614/
https://ncbi.nlm.nih.gov/pubmed/32191428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00655
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