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Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice
Aging is the major risk factor for many metabolic chronic diseases. Several metabolic pathways suffer a progressive impairment during aging including body composition and insulin resistance which are associated to autophagy dysfunction and increased inflammation. Many of these alterations are aggrav...
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| Publicado no: | GeroScience |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7206474/ https://ncbi.nlm.nih.gov/pubmed/31975052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00151-6 |
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