NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice

While NLRP3‐inflammasome has been implicated in cardiovascular diseases, its role in physiological cardiac aging is largely unknown. During aging, many alterations occur in the organism, which are associated with progressive impairment of metabolic pathways related to insulin resistance, autophagy d...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Marín‐Aguilar, Fabiola, Lechuga‐Vieco, Ana V., Alcocer‐Gómez, Elísabet, Castejón‐Vega, Beatriz, Lucas, Javier, Garrido, Carlos, Peralta‐Garcia, Alejandro, Pérez‐Pulido, Antonio J., Varela‐López, Alfonso, Quiles, José L., Ryffel, Bernhard, Flores, Ignacio, Bullón, Pedro, Ruiz‐Cabello, Jesús, Cordero, Mario D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974709/
https://ncbi.nlm.nih.gov/pubmed/31625260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13050
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