NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice

While NLRP3‐inflammasome has been implicated in cardiovascular diseases, its role in physiological cardiac aging is largely unknown. During aging, many alterations occur in the organism, which are associated with progressive impairment of metabolic pathways related to insulin resistance, autophagy d...

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Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Marín‐Aguilar, Fabiola, Lechuga‐Vieco, Ana V., Alcocer‐Gómez, Elísabet, Castejón‐Vega, Beatriz, Lucas, Javier, Garrido, Carlos, Peralta‐Garcia, Alejandro, Pérez‐Pulido, Antonio J., Varela‐López, Alfonso, Quiles, José L., Ryffel, Bernhard, Flores, Ignacio, Bullón, Pedro, Ruiz‐Cabello, Jesús, Cordero, Mario D.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974709/
https://ncbi.nlm.nih.gov/pubmed/31625260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13050
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