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NLRP3 inflammasome suppression improves longevity and prevents cardiac aging in male mice

While NLRP3‐inflammasome has been implicated in cardiovascular diseases, its role in physiological cardiac aging is largely unknown. During aging, many alterations occur in the organism, which are associated with progressive impairment of metabolic pathways related to insulin resistance, autophagy d...

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Bibliografische gegevens
Gepubliceerd in:Aging Cell
Hoofdauteurs: Marín‐Aguilar, Fabiola, Lechuga‐Vieco, Ana V., Alcocer‐Gómez, Elísabet, Castejón‐Vega, Beatriz, Lucas, Javier, Garrido, Carlos, Peralta‐Garcia, Alejandro, Pérez‐Pulido, Antonio J., Varela‐López, Alfonso, Quiles, José L., Ryffel, Bernhard, Flores, Ignacio, Bullón, Pedro, Ruiz‐Cabello, Jesús, Cordero, Mario D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974709/
https://ncbi.nlm.nih.gov/pubmed/31625260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13050
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