Blockade of the NLRP3 inflammasome improves metabolic health and lifespan in obese mice

Aging is the major risk factor for many metabolic chronic diseases. Several metabolic pathways suffer a progressive impairment during aging including body composition and insulin resistance which are associated to autophagy dysfunction and increased inflammation. Many of these alterations are aggrav...

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Udgivet i:GeroScience
Main Authors: Cañadas-Lozano, Diego, Marín-Aguilar, Fabiola, Castejón-Vega, Beatriz, Ryffel, Bernhard, Navarro-Pando, José M., Ruiz-Cabello, Jesús, Alcocer-Gómez, Elísabet, Bullón, Pedro, Cordero, Mario D.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206474/
https://ncbi.nlm.nih.gov/pubmed/31975052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-019-00151-6
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