Downregulation of FOXO3a by DNMT1 promotes breast cancer stem cell properties and tumorigenesis

Breast cancer stem cells (BCSCs) are tumor initiating cells that can self-renew and are highly tumorigenic and chemoresistant. Therefore, the identification of factors critical for BCSC function is vital for the development of therapies. Here, we report that DNMT1-mediated FOXO3a promoter hypermethy...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Liu, Hao, Song, Ying, Qiu, Huishi, Liu, Yanzhen, Luo, Kai, Yi, Yanmei, Jiang, Guanmin, Lu, Minying, Zhang, Zhijie, Yin, Jiang, Zeng, Shanshan, Chen, Xiangzhou, Deng, Min, Jia, Xiaoting, Gu, Yixue, Chen, Danyang, Zheng, Guopei, He, Zhimin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206060/
https://ncbi.nlm.nih.gov/pubmed/31296961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0389-3
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados