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Functional interplay between p53 and Δ133p53 in adaptive stress response

Apart from its well-known prodeath activity, p53 is also implicated in promoting cell survival. How p53 can mediate such seemingly opposing effects is largely unclear. We report here a novel mechanism in which p53-mediated proapoptosis is switched to antiapoptosis via its interaction with a p53 isof...

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Publicat a:Cell Death Differ
Autors principals: Gong, Lu, Pan, Xiao, Abali, Gamze K., Little, John B., Yuan, Zhi-Min
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7206045/
https://ncbi.nlm.nih.gov/pubmed/31659281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0445-z
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