The inhibitory effect of compound ChlA-F on human bladder cancer cell invasion can be attributed to its blockage of SOX2 protein

Sex-determining region Y-box 2 (SOX2), a well-known stemness biomarker, is highly expressed in a variety of cancers, including human highly invasive bladder cancer (BC). However, the role of SOX2 may vary in different kinds of malignancy. In the present study, we discovered that ChlA-F, a novel conf...

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Udgivet i:Cell Death Differ
Main Authors: Hua, Xiaohui, Huang, Maowen, Deng, Xu, Xu, Jiheng, Luo, Yisi, Xie, Qipeng, Xu, Jiawei, Tian, Zhongxian, Li, Jingxia, Zhu, Junlan, Huang, Chao, Zhao, Qin-shi, Huang, Haishan, Huang, Chuanshu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205984/
https://ncbi.nlm.nih.gov/pubmed/31243344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0377-7
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