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PTBP1 modulates osteosarcoma chemoresistance to cisplatin by regulating the expression of the copper transporter SLC31A1

Chemoresistance is the main obstacle of treatment in patients with osteosarcoma. RNA‐binding protein PTBP1 has been identified as an oncogene in various cancers. However, the role of PTBP1 in osteosarcoma, especially in chemoresistant osteosarcoma, and the underlying mechanism remain unclear. In thi...

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Détails bibliographiques
Publié dans:J Cell Mol Med
Auteurs principaux: Cheng, Cheng, Ding, Qiuyue, Zhang, Zhicai, Wang, Shangyu, Zhong, Binlong, Huang, Xin, Shao, Zengwu
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205786/
https://ncbi.nlm.nih.gov/pubmed/32207235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15183
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