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PTBP1 modulates osteosarcoma chemoresistance to cisplatin by regulating the expression of the copper transporter SLC31A1

Chemoresistance is the main obstacle of treatment in patients with osteosarcoma. RNA‐binding protein PTBP1 has been identified as an oncogene in various cancers. However, the role of PTBP1 in osteosarcoma, especially in chemoresistant osteosarcoma, and the underlying mechanism remain unclear. In thi...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Cheng, Cheng, Ding, Qiuyue, Zhang, Zhicai, Wang, Shangyu, Zhong, Binlong, Huang, Xin, Shao, Zengwu
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205786/
https://ncbi.nlm.nih.gov/pubmed/32207235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15183
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