GFRA1 promotes cisplatin-induced chemoresistance in osteosarcoma by inducing autophagy

Recent progress in chemotherapy has significantly increased its efficacy, yet the development of chemoresistance remains a major drawback. In this study, we show that GFRA1/GFRα1 (GDNF family receptor α 1), contributes to cisplatin-induced chemoresistance by regulating autophagy in osteosarcoma. We...

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Bibliographic Details
Published in:Autophagy
Main Authors: Kim, Mihwa, Jung, Ji-Yeon, Choi, Seungho, Lee, Hyunseung, Morales, Liza D., Koh, Jeong-Tae, Kim, Sun Hun, Choi, Yoo-Duk, Choi, Chan, Slaga, Thomas J., Kim, Won Jae, Kim, Dae Joon
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
Subjects:
Basic Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240831/
https://ncbi.nlm.nih.gov/pubmed/27754745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1239676
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