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Senescence Elicits Stemness: A Surprising Mechanism for Cancer Relapse

Cellular senescence is traditionally viewed as a permanent form of cell cycle arrest that restrains tumorigenesis. In a recent study in Nature, however, Milanovic et al. (2018) challenge this conventional view, showing that senescence can counterintuitively promote cancer sternness and tumor aggress...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Dou, Zhixun, Berger, Shelley L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205594/
https://ncbi.nlm.nih.gov/pubmed/29617638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2018.03.009
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