Cytoplasmic chromatin triggers inflammation in senescence and cancer

Chromatin is traditionally viewed as a nuclear entity that regulates gene expression and silencing(1–3). However, we recently discovered the presence of cytoplasmic chromatin fragments that pinch off from intact nuclei of primary cells during senescence(4,5), a form of terminal cell cycle arrest ass...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nature
Main Authors: Dou, Zhixun, Ghosh, Kanad, Vizioli, Maria Grazia, Zhu, Jiajun, Sen, Payel, Wangensteen, Kirk J., Simithy, Johayra, Lan, Yemin, Lin, Yanping, Zhou, Zhuo, Capell, Brian C., Xu, Caiyue, Xu, Mingang, Kieckhaefer, Julia E., Jiang, Tianying, Shoshkes-Carmel, Michal, Ahasan Al Tanim, K.M., Barber, Glen N., Seykora, John T., Millar, Sarah E., Kaestner, Klaus H., Garcia, Benjamin A., Adams, Peter D., Berger, Shelley L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850938/
https://ncbi.nlm.nih.gov/pubmed/28976970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24050
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados