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Discovery of ubonodin, an antimicrobial lasso peptide active against members of the Burkholderia cepacia complex
We report the heterologous expression, structure, and antimicrobial activity of a lasso peptide, ubonodin, encoded in the genome of Burkholderia ubonensis. The topology of ubonodin is unprecedented amongst lasso peptides with 18 of its 28 amino acids found in the mechanically-bonded loop segment. Ub...
Shranjeno v:
| izdano v: | Chembiochem |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7205569/ https://ncbi.nlm.nih.gov/pubmed/31765515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900707 |
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