Φορτώνει......
Combining molecular dynamics simulations with small-angle X-ray and neutron scattering data to study multi-domain proteins in solution
Many proteins contain multiple folded domains separated by flexible linkers, and the ability to describe the structure and conformational heterogeneity of such flexible systems pushes the limits of structural biology. Using the three-domain protein TIA-1 as an example, we here combine coarse-grained...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | PLoS Comput Biol |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7205321/ https://ncbi.nlm.nih.gov/pubmed/32339173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007870 |
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