Hyd ubiquitinates the NF-κB co-factor Akirin to operate an effective immune response in Drosophila

The Immune Deficiency (IMD) pathway in Drosophila melanogaster is activated upon microbial challenge with Gram-negative bacteria to trigger the innate immune response. In order to decipher this nuclear factor κB (NF-κB) signaling pathway, we undertook an in vitro RNAi screen targeting E3 ubiquitin l...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: Cammarata-Mouchtouris, Alexandre, Nguyen, Xuan-Hung, Acker, Adrian, Bonnay, François, Goto, Akira, Orian, Amir, Fauvarque, Marie-Odile, Boutros, Michael, Reichhart, Jean-Marc, Matt, Nicolas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205318/
https://ncbi.nlm.nih.gov/pubmed/32339205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008458
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