Akirins, highly conserved nuclear proteins, required for NF-κB dependent gene expression in Drosophila and mice

During a genome-wide RNAi screen, we isolated CG8580 as a gene involved in the innate immune response of Drosophila. CG8580, which we named Akirin, acts in parallel with the NF-κB transcription factor downstream of the Imd pathway and was required for defense against Gram-negative bacteria. Akirin i...

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Detalhes bibliográficos
Main Authors: Goto, Akira, Matsushita, Kazufumi, Gesellchen, Viola, Chamy, Laure El, Kuttenkeuler, David, Takeuchi, Osamu, Hoffmann, Jules A., Akira, Shizuo, Boutros, Michael, Reichhart, Jean-Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680477/
https://ncbi.nlm.nih.gov/pubmed/18066067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1543
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