Akirin2 is critical for inducing inflammatory genes by bridging IκB-ζ and the SWI/SNF complex

Transcription of inflammatory genes in innate immune cells is coordinately regulated by transcription factors, including NF-κB, and chromatin modifiers. However, it remains unclear how microbial sensing initiates chromatin remodeling. Here, we show that Akirin2, an evolutionarily conserved nuclear p...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Tartey, Sarang, Matsushita, Kazufumi, Vandenbon, Alexis, Ori, Daisuke, Imamura, Tomoko, Mino, Takashi, Standley, Daron M, Hoffmann, Jules A, Reichhart, Jean-Marc, Akira, Shizuo, Takeuchi, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253523/
https://ncbi.nlm.nih.gov/pubmed/25107474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488447
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