NFATC4 promotes quiescence and chemotherapy resistance in ovarian cancer

Development of chemotherapy resistance is a major problem in ovarian cancer. One understudied mechanism of chemoresistance is the induction of quiescence, a reversible nonproliferative state. Unfortunately, little is known about regulators of quiescence. Here, we identify the master transcription fa...

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Pubblicato in:JCI Insight
Autori principali: Cole, Alexander J., Iyengar, Mangala, Panesso-Gómez, Santiago, O’Hayer, Patrick, Chan, Daniel, Delgoffe, Greg M., Aird, Katherine M., Yoon, Euisik, Bai, Shoumei, Buckanovich, Ronald J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205258/
https://ncbi.nlm.nih.gov/pubmed/32182216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131486
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