Leptin receptor–expressing nucleus tractus solitarius neurons suppress food intake independently of GLP1 in mice

Leptin receptor–expressing (LepRb-expressing) neurons of the nucleus tractus solitarius (NTS; LepRb(NTS) neurons) receive gut signals that synergize with leptin action to suppress food intake. NTS neurons that express preproglucagon (Ppg) (and that produce the food intake–suppressing PPG cleavage pr...

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Pubblicato in:JCI Insight
Autori principali: Cheng, Wenwen, Ndoka, Ermelinda, Hutch, Chelsea, Roelofs, Karen, MacKinnon, Andrew, Khoury, Basma, Magrisso, Jack, Kim, Ki Suk, Rhodes, Christopher J., Olson, David P., Seeley, Randy J., Sandoval, Darleen, Myers, Martin G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205255/
https://ncbi.nlm.nih.gov/pubmed/32182221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134359
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