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Leptin Signaling in the Medial Nucleus Tractus Solitarius Reduces Food Seeking and Willingness to Work for Food

The adipose-derived hormone leptin signals in the medial nucleus tractus solitarius (mNTS) to suppress food intake, in part, by amplifying within-meal gastrointestinal (GI) satiation signals. Here we show that mNTS leptin receptor (LepRb) signaling also reduces appetitive and motivational aspects of...

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Detalles Bibliográficos
Main Authors: Kanoski, Scott E, Alhadeff, Amber L, Fortin, Samantha M, Gilbert, Jennifer R, Grill, Harvey J
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895238/
https://ncbi.nlm.nih.gov/pubmed/24002186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.235
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