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Glycemic effect of pancreatic preproglucagon in mouse sleeve gastrectomy

Intestinally derived glucagon-like peptide-1 (GLP-1), encoded by the preproglucagon (Gcg) gene, is believed to function as an incretin. However, our previous work questioned this dogma and demonstrated that pancreatic peptides rather than intestinal Gcg peptides, including GLP-1, are a primary regul...

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Bibliografske podrobnosti
izdano v:JCI Insight
Main Authors: Kim, Ki-Suk, Hutch, Chelsea R., Wood, Landon, Magrisso, Irwin J., Seeley, Randy J., Sandoval, Darleen A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824314/
https://ncbi.nlm.nih.gov/pubmed/31619587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129452
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