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Glycemic effect of pancreatic preproglucagon in mouse sleeve gastrectomy

Intestinally derived glucagon-like peptide-1 (GLP-1), encoded by the preproglucagon (Gcg) gene, is believed to function as an incretin. However, our previous work questioned this dogma and demonstrated that pancreatic peptides rather than intestinal Gcg peptides, including GLP-1, are a primary regul...

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Dettagli Bibliografici
Pubblicato in:JCI Insight
Autori principali: Kim, Ki-Suk, Hutch, Chelsea R., Wood, Landon, Magrisso, Irwin J., Seeley, Randy J., Sandoval, Darleen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824314/
https://ncbi.nlm.nih.gov/pubmed/31619587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129452
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