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The role of pancreatic preproglucagon in glucose homeostasis in mice

Glucagon-like peptide 1 (GLP-1) is necessary for normal gluco-regulation, and it has been widely presumed that this function reflects the actions of GLP-1 released from enteroendocrine L-cells. To test the relative importance of intestinal vs. pancreatic sources of GLP-1 for physiological regulation...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Chambers, Adam P., Sorrell, Joyce, Haller, April, Roelofs, Karen, Hutch, Chelsea R., Kim, Ki-Suk, Gutierrez-Aguilar, Ruth, Li, Bailing, Drucker, Daniel J., D’Alessio, David A., Seeley, Randy J., Sandoval, Darleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5385998/
https://ncbi.nlm.nih.gov/pubmed/28325479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.02.008
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