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Structural insights into electrophile irritant sensing by the human TRPA1 channel
Transient receptor potential channel subfamily A member 1 (TRPA1) is a Ca(2+)-permeable cation channel that serves as one of the primary sensors of environmental irritants and noxious substances. Many TRPA1 agonists are electrophiles that are recognized by TRPA1 via covalent bond modifications of sp...
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| Publicado en: | Neuron |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7205012/ https://ncbi.nlm.nih.gov/pubmed/31866091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.11.023 |
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