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Gating and calcium-sensing mechanisms of TRPA1 channels revealed. Commentary on “Irritant-evoked activation and calcium modulation of the TRPA1 receptor”
Novel structures of the human TRPA1 channel were determined in the presence of the agonist iodoacetamide and the antagonist A-967079, to reveal the open and closed states of the channel, respectively. The structures further revealed the location of Ca(2+) modulatory site that is likely conserved amo...
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| Publicat a: | Cell Calcium |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7530115/ https://ncbi.nlm.nih.gov/pubmed/32858446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2020.102278 |
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