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Ethanol withdrawal hastens the aging of cytochrome c oxidase.

We investigated whether abrupt ethanol withdrawal (EW) age-specifically inhibits a key mitochondrial enzyme, cytochrome c oxidase (COX), and whether estrogen mitigates this problem. We also tested whether this possible effect of EW involves a substrate (cytochrome c) deficiency that is associated wi...

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Bibliographic Details
Published in:Neurobiol Aging
Main Authors: Jung, Marianna E., Ju, Xiaohua, Metzger, Daniel B., Simpkins, James W.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7204395/
https://ncbi.nlm.nih.gov/pubmed/21439684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2011.02.002
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