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The Role of Presenilin-1 in the Excitotoxicity of Ethanol Withdrawal
Presenilin-1 (PS1) is a core component of γ-secretase that is involved in neurodegeneration. We have previously shown that PS1 interacts with a mitogen-activated protein kinase [(MAPK) jun-NH2-terminal-kinase], and another MAPK (p38) is activated by ethanol withdrawal (EW), abrupt termination from c...
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| Pubblicato in: | J Pharmacol Exp Ther |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4998674/ https://ncbi.nlm.nih.gov/pubmed/27278235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.233361 |
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