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Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis
Mitochondria physically associate with the endoplasmic reticulum to coordinate interorganelle calcium transfer and regulate fundamental cellular processes, including inflammation. Deregulated endoplasmic reticulum–mitochondria cross-talk can occur in cystic fibrosis, contributing to hyperinflammatio...
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| Veröffentlicht in: | Sci Adv |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Association for the Advancement of Science
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7202873/ https://ncbi.nlm.nih.gov/pubmed/32494695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax9093 |
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