Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis

Mitochondria physically associate with the endoplasmic reticulum to coordinate interorganelle calcium transfer and regulate fundamental cellular processes, including inflammation. Deregulated endoplasmic reticulum–mitochondria cross-talk can occur in cystic fibrosis, contributing to hyperinflammatio...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Adv
Main Authors: Rimessi, Alessandro, Pozzato, Chiara, Carparelli, Lorenzo, Rossi, Alice, Ranucci, Serena, De Fino, Ida, Cigana, Cristina, Talarico, Anna, Wieckowski, Mariusz R., Ribeiro, Carla M. P., Trapella, Claudio, Rossi, Giacomo, Cabrini, Giulio, Bragonzi, Alessandra, Pinton, Paolo
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2020
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202873/
https://ncbi.nlm.nih.gov/pubmed/32494695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax9093
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