Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis

Mitochondria physically associate with the endoplasmic reticulum to coordinate interorganelle calcium transfer and regulate fundamental cellular processes, including inflammation. Deregulated endoplasmic reticulum–mitochondria cross-talk can occur in cystic fibrosis, contributing to hyperinflammatio...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: Rimessi, Alessandro, Pozzato, Chiara, Carparelli, Lorenzo, Rossi, Alice, Ranucci, Serena, De Fino, Ida, Cigana, Cristina, Talarico, Anna, Wieckowski, Mariusz R., Ribeiro, Carla M. P., Trapella, Claudio, Rossi, Giacomo, Cabrini, Giulio, Bragonzi, Alessandra, Pinton, Paolo
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202873/
https://ncbi.nlm.nih.gov/pubmed/32494695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax9093
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