Pharmacological modulation of mitochondrial calcium uniporter controls lung inflammation in cystic fibrosis

Mitochondria physically associate with the endoplasmic reticulum to coordinate interorganelle calcium transfer and regulate fundamental cellular processes, including inflammation. Deregulated endoplasmic reticulum–mitochondria cross-talk can occur in cystic fibrosis, contributing to hyperinflammatio...

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Sparad:
Bibliografiska uppgifter
I publikationen:Sci Adv
Huvudupphovsmän: Rimessi, Alessandro, Pozzato, Chiara, Carparelli, Lorenzo, Rossi, Alice, Ranucci, Serena, De Fino, Ida, Cigana, Cristina, Talarico, Anna, Wieckowski, Mariusz R., Ribeiro, Carla M. P., Trapella, Claudio, Rossi, Giacomo, Cabrini, Giulio, Bragonzi, Alessandra, Pinton, Paolo
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Association for the Advancement of Science 2020
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202873/
https://ncbi.nlm.nih.gov/pubmed/32494695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax9093
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