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RIG-I-like receptor activation drives type I IFN and antiviral signaling to limit Hantaan orthohantavirus replication
Pathogenic hantaviruses, genus Orthohantaviridae, are maintained in rodent reservoirs with zoonotic transmission to humans occurring through inhalation of rodent excreta. Hantavirus disease in humans is characterized by localized vascular leakage and elevated levels of circulating proinflammatory cy...
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| Gepubliceerd in: | PLoS Pathog |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7202661/ https://ncbi.nlm.nih.gov/pubmed/32330200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008483 |
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