Leptin signaling and the intervertebral disc: Sex dependent effects of leptin receptor deficiency and Western diet on the spine in a type 2 diabetes mouse model

Type 2 diabetes and obesity are associated with back pain in juveniles and adults and are implicated in intervertebral disc (IVD) degeneration. Hypercaloric Western diets are associated with both obesity and type 2 diabetes. The objective of this study was to determine if obesity and type 2 diabetes...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Natelson, Devorah M., Lai, Alon, Krishnamoorthy, Divya, Hoy, Robert C., Iatridis, James C., Illien-Jünger, Svenja
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202633/
https://ncbi.nlm.nih.gov/pubmed/32374776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0227527
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