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MicroRNA-375 exacerbates knee osteoarthritis through repressing chondrocyte autophagy by targeting ATG2B
Objective: This study aimed to explore the underlying mechanism of miR-375 in exacerbating osteoarthritis (OA). Results: MiR-375 expression were upregulated in OA cartilage tissues, whereas ATG2B expression was decreased. MiR-375 targeted ATG2B 3’ UTR and inhibited its expression in the chondrocytes...
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| Publicat a: | Aging (Albany NY) |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7202526/ https://ncbi.nlm.nih.gov/pubmed/32335541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103073 |
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