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MicroRNA-128a represses chondrocyte autophagy and exacerbates knee osteoarthritis by disrupting Atg12

Chondrocyte loss is a prominent feature of osteoarthritis (OA). Autophagy is indispensable in maintaining the metabolic activities of cells exposed to deleterious stress. The contribution of microRNA signaling to chondrocyte autophagy in OA development remains elusive. We uncovered an association be...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Lian, Wei-Shiung, Ko, Jih-Yang, Wu, Re-Weng, Sun, Yi-Chih, Chen, Yu-Shan, Wu, Shin-Long, Weng, Lin-Hsiu, Jahr, Holger, Wang, Feng-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134128/
https://ncbi.nlm.nih.gov/pubmed/30206206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0994-y
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