MicroRNA-375 exacerbates knee osteoarthritis through repressing chondrocyte autophagy by targeting ATG2B

Objective: This study aimed to explore the underlying mechanism of miR-375 in exacerbating osteoarthritis (OA). Results: MiR-375 expression were upregulated in OA cartilage tissues, whereas ATG2B expression was decreased. MiR-375 targeted ATG2B 3’ UTR and inhibited its expression in the chondrocytes...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Li, Hongxing, Li, Zhiling, Pi, Yigang, Chen, Yang, Mei, Lin, Luo, Yong, Xie, Jingping, Mao, Xinzhan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202526/
https://ncbi.nlm.nih.gov/pubmed/32335541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103073
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