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High‐grade mesenchymal pancreatic ductal adenocarcinoma drives stromal deactivation through CSF‐1

Pancreatic ductal adenocarcinoma (PDAC) is characterized by an abundance of stroma. Multiple molecular classification efforts have identified a mesenchymal tumor subtype that is consistently characterized by high‐grade growth and poor clinical outcome. The relation between PDAC stroma and tumor subt...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Steins, Anne, van Mackelenbergh, Madelaine G, van der Zalm, Amber P, Klaassen, Remy, Serrels, Bryan, Goris, Sandrine G, Kocher, Hemant M, Waasdorp, Cynthia, de Jong, Joan H, Tekin, Cansu, Besselink, Marc G, Busch, Olivier R, van de Vijver, Marc J, Verheij, Joanne, Dijk, Frederike, van Tienhoven, Geertjan, Wilmink, Johanna W, Medema, Jan Paul, van Laarhoven, Hanneke WM, Bijlsma, Maarten F
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7202203/
https://ncbi.nlm.nih.gov/pubmed/32173982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948780
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