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TMEM135 regulates primary ciliogenesis through modulation of intracellular cholesterol distribution
Recent evidence has linked the lysosomal cholesterol accumulation in Niemann–Pick type C1 with anomalies associated with primary ciliogenesis. Here, we report that perturbed intracellular cholesterol distribution imposed by lysosomal cholesterol accumulation during TMEM135 depletion is closely assoc...
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| Publié dans: | EMBO Rep |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7202201/ https://ncbi.nlm.nih.gov/pubmed/32157776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948901 |
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