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Brd4 and P300 confer transcriptional competency during zygotic genome activation
The awakening of the genome after fertilization is a cornerstone of animal development. However, the mechanisms that activate the silent genome after fertilization are poorly understood. Here, we show that transcriptional competency is regulated by Brd4 and p300-dependent histone acetylation in zebr...
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| Yayımlandı: | Dev Cell |
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| Asıl Yazarlar: | , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7201981/ https://ncbi.nlm.nih.gov/pubmed/31211993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.05.037 |
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