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Extended half-life target module for sustainable UniCAR T-cell treatment of STn-expressing cancers
BACKGROUND: Adapter chimeric antigen receptor (CAR) approaches have emerged has promising strategies to increase clinical safety of CAR T-cell therapy. In the UniCAR system, the safety switch is controlled via a target module (TM) which is characterized by a small-size and short half-life. The rapid...
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| Publicado no: | J Exp Clin Cancer Res |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7201957/ https://ncbi.nlm.nih.gov/pubmed/32370811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01572-4 |
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