Caricamento...
The N-terminal domain in TRPM2 channel is a conserved nucleotide binding site
This study by Tóth et al. has defined that the N-terminal MHR1/2 domain is a conserved ADPR binding site in TRPM2 from ancient cnidarians to vertebrate, and that it is the key ligand binding site for invertebrate TRPM2 channel activation by ADPR, the same as observed in human and zebrafish TRPM2.
Salvato in:
| Pubblicato in: | J Gen Physiol |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Rockefeller University Press
2020
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7201883/ https://ncbi.nlm.nih.gov/pubmed/32282890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201912555 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|